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Innovations in MSI Detection: Unmasking a New Testing Solution

Innovations in MSI Detection: Unmasking a New Testing Solution

24 October, 2023 2:00 pm-3:00 pm (CEST)

Microsatellite instability (MSI) is an evolving biomarker for colorectal cancer (CRC) detection and treatment, with crucial diagnostic, prognostic, and predictive implications – to identify patients with Lynch syndrome, determine the prognosis of Stage II colon cancer patients and predict patient response to immunotherapy. Different approaches have been developed for MSI detection.

In this webinar, we will compare the different methods that are currently being used for MSI testing, and introduce a novel, one-step PCR melting curve analysis featuring rapid turnaround time and high sensitivity to determine MSI status, which shows high concordance rate with fragment analysis MSI.

What will you learn?

Comparison between technologies to measure MSI 
AmoyDx MSI detection solution
Experience sharing in MSI testing practice

Featured Speakers

Dr. Dario de Biase
Associate Professor of General Pathology, Department of Pharmacy and Biotechnology, University of Bologna

Dario de Biase is an Associate Professor of General Pathology in the Department of Pharmacy and Biotechnology at the University of Bologna, Italy. His interests lie in general pathology, molecular pathology, neoplastic pathology, genetics of neoplasms, and cellular and molecular biology. 

A/Prof de Biase completed his Doctoral Degree in oncology and experimental pathology at Bellaria Hospital, University of Bologna, before completing research fellowships in the Interdepartmental Cancer Research Centre, Department of Hematology and Experimental Oncology, and Department of Experimental Medicine at the University of Bologna. Integral in the institution’s faculty, teaching, and research, A/Prof de Biase has supervised over 60 theses in general pathology. Furthermore, his research covers the analysis of predictive/prognostic/diagnostic markers in solid tumors, collaborating with multiple disciplines in Azienda Unità Sanitaria Locale (AUSL) of Bologna.

A/Prof de Biase is a member of the Emiliano-Romagnolo Project in Neuro Oncology (PERNO), Scientific Committee for the TissuEus International Congress, and the regional external quality control group for the immunohistochemical determination of markers predictive of therapy in breast cancer and of molecular tests predictive of personalized oncological therapies. He an author of over 150 manus in peer-reviewed journals. 

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