The AmoyDx® HANDLE Melanoma NGS Panel is an advanced next-generation sequencing (NGS) assay designed to qualitatively detect single nucleotide variants (SNVs), insertions, and deletions (InDels) within pivotal melanoma tumor genes, utilizing DNA extracted from formalin-fixed paraffin-ded (FFPE) tumor tissue specimens.
Mutations( Hover over each mutational type to highlight genes covered )
All
BRAF
BRAF
SNV/INDELS
CTNNB1
CTNNB1
SNV/INDELS
GNA11
GNA11
SNV/INDELS
GNAQ
GNAQ
SNV/INDELS
HRAS
HRAS
SNV/INDELS
KIT
KIT
SNV/INDELS
KRAS
KRAS
SNV/INDELS
NRAS
NRAS
SNV/INDELS
TERT
TERT
SNV
Comprehensive analysis of 9 key genes in Melanoma cancer
Decentralized kit solution with ease of use
Short turnaround time
within 3 days
Cost-effective & require less equipment
Specifications
Sample type
FFPE tissue
Alterations Detected
SNV, InDel
DNA input
30-100 ng (50 ng is recommended)
Data output per sample
25 Mb/sample, (0.025 GB)
Sequencer
Illumina NextSeq 500/550, MiSeq/MiSeqDx, iSeq 100 (PE150)
TAT for library preparationn
5 hours (hands-on time 1 hour)
TAT from sample to report
3 days
Inquiry