Human Papillomavirus (HPV) Genotyping Detection Kit
PCR
Real-time PCR Assays
100 copies/rxn
Sensitivity
100%
100%
Accuracy
Product Description

Human Papillomavirus (HPV) Genotyping Detection Kit

Real-Time PCR Assay for Genotyping of 19 High-risk HPVs and 2 low-risk HPVs

Human papillomavirus (HPV) is a sexually transmitted DNA virus that establishes infection in squamous epithelialcells in the human body. There are more than 200 types of HPV, which can be classified into high or low-risktypes depending upon their oncogenic potentials.High-risk HPVs also called oncogenic HPVs, which have been confirmed to cause cancer, such as HPV16 and 18.And some HPVs are possibly carcinogenic to humans, like HPV26, 53, 66, 70, 73 and 82, that be classified as high-risk or probably high-risk HPVs. Low-risk HPVs can cause genital warts and low-grade changes in thecells, but rarely cause cancer, such as HPV6 and 11.

19 high-risk HPV types:

HPV16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 70, 73, and 82.

2 low-risk HPV types:

HPV6 and 11.

Technological Principles:

The kit is designed for a specific amplification of L1 gene in HPV DNA. The targeted region of HPV DNA is amplified by several specific primers and detected by novel fluorescence probes. A non-rivalry internal control is added in the HPV DNA detection system to reveal the presence of PCR inhibitors and monitor the accuracy of experimental operation.

Testing Procedure
Compatible Sample Types:Cervical exfoliated cells or Urogenital tract secretion samples
Compatible Real-time PCR Instrument
ABI 7500
Bio-Rad CFX96
LightCycler 480 II
SLAN-96S
Stratagene Mx3000P™
Other Info.

To order, please contact sales@amoydx.com.

AmoyDx HPV Genotyping Detection Kit provides reagents to perform assays for 48 tests:

Product Name Type Size (test/kit) Storage  Cat. No.
AmoyDx® HPV Genotyping Detection Kit Bulk 48 -20±5℃ 8.01.25803W048E


Publications
1. Vošmik, M., et al. "HPV Status and Mutation Analysis Using Multiparallel Sequencing in Distal Oesophageal and Gastro-oesophageal Junction Adenocarcinomas." Folia biologica 64.2 (2018): 41-45.
2. Nikakhtar, Zahra, et al. "The efficacy of vaginal suppository based on myrtle in patients with cervicovaginal human papillomavirus infection: A randomized, double‐blind, placebo trial." Phytotherapy research 32.10 (2018): 2002-2008.
3. Laco, Jan, et al. "SMARCB1/INI1-deficient sinonasal carcinoma shows methylation of RASSF1 gene: A clinicopathological, immunohistochemical and molecular genetic study of a recently described entity." Pathology-Research and Practice 213.2 (2017): 133-142.
4. Biesaga, Beata, et al. "The prevalence of HPV infection in rectal cancer–Report from South–Central Poland (Cracow region)." Pathology-Research and Practice 215.9 (2019): 152513.
5. Hladíková, Kamila, et al. "Tumor-infiltrating B cells affect the progression of oropharyngeal squamous cell carcinoma via cell-to-cell interactions with CD8+ T cells." Journal for immunotherapy of cancer 7.1 (2019): 261.

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